Leonardo's Heart Valve

[arunraje]

Leonardo's studies of cardiovascular systems in more than 50 surviving pages from 2 phases of his research (around 1508—1509 to 1513), are a clear demonstration of his observational genius and progressive deduction of cardiac mechanics and the vascular system.

He carried out a detailed hemodynamic study of the aortic valve motion and the role of sinus Valsalva in the closure dynamics of the aortic valve, and he accurately correlated the formation of vortices with the separation of a retarded (shear) layer from the lips of the leaflets. In-vivo verification of vortex formation in the sinus of Valsalva during the systolic phase awaited the application of modern phase-averaged magnetic resonance imaging techniques. Did Leonardo actually build the glass model he twice mentioned, thus performing the first scientific flow visualization of impulsive vortex formation or other fluid mechanical phenomena? Evidence in support of this possibility can be found in both the unusually schematic style he employed for the suite of drawings and the recent flow imaging results obtained in our laboratory through laser based imaging technique.

A replica of the heart valve designed by Leonardo da Vinci was created by Professor Gharib, Dr. Arash Kheradvar (MD), Mr. Richard P. Gerhart (Caltech Glass shop), and Mr. David Kremers and became part of the exhibit, Leonardo Da Vinci: Experience, Experiment, and Design, at the Victoria and Albert Museum in London (14 September 2006 - 7 January 2007).

http://www.gharib.caltech.edu/art_and_s ... elease.pdf

Publication
Gharib M, Kremers D, Koochesfahani MM, et al., Leonardo's vision of flow visualization, EXP FLUIDS 33 (1): 219-223 JUL 2002

http://www.gharib.caltech.edu/art_and_s ... index.html